A prospective study on efficacy of Platelet Rich Fibrin (PRF) in the management of trophic ulcers of leprosy

Introduction: Trophic ulcers are the major cause of disability in leprosy patients. The disease imposes a social stigma and economic burden these patients which interferes with regular treatment resulting defaulters. Chronicity ulcer complications like osteomyelitis malignancy became an ever challenging task for treating physician. Newer modalities on search decreasing duration preventing recurrence trophic ulcers. Platelet rich fibrin (PRF) is platelet concentrate provides rapid wound healing through release various growth factors. Aim: To evaluate efficacy topical gel non-healing leprosy. Material Methods: Based inclusion exclusion criteria, 10 having more than six weeks were enrolled study. Following surgical debridement, autologous was placed over bed covered secondary dressing. Procedure repeated weekly up to four weeks. Results: At end weeks, complete seen five (50%).Other achieved 80-90% reduction volume ulcer. percentage mean 96.31%. Conclusion: Early diagnosis proper management neuritis will prevent has become inexpensive, easily available option less side effects